Korkovník amurský (Phellodendron amurense)
Korkovník amurský patří do rodu Rutaceae. Původem pochází z Koreje, severní Číny (řeka Amur v blízkosti Sibiře) a Japonska. Jeho deriváty se používají na zmírnění zánětu, bolesti a na ekzém. Moderní věda prokázala jeho účinnost jako protizánětlivé (1, 2, 3) a anti-mikrobiální činidlo (4, 5, 6).
Reference:
1. Cuéllar MJ, et al., Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders. Fitoterapia. 2001 Mar;72(3):221-9.
2. Park YK, Chung YS, Kim YS, Kwon OY, Joh TH. Inhibition of gene expression and production of iNOS and TNF-alpha in LPS-stimulated microglia by methanol extract of Phellodendri cortex. Int Immunopharmacol. 2007 Jul;7(7):955-62.
3. Xian YF, Mao QQ, Ip SP, Lin ZX, Che CT. Comparison on the anti-inflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoyl-phorbol-13-acetate-induced ear edema in mice. J Ethnopharmacol. 2011 Oct 11;137(3):1425-30.
4. Quan H,et al. Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole.
5. Yu HH, et al., Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin resistant Staphylococcus aureus. J Med Food. 2005;8(4):454-61.
6. Park KS, Kang KC, Kim JH, Adams DJ, Johng TN, Paik YK. Differential inhibitory effects of protoberberines on sterol and chitin biosyntheses in Candida albicans. J Antimicrob Chemother. 1999 May;43(5):667-74.
